Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2014
Exophiala dermatitidis pneumonia successfully treated with long-term itraconazole therapy.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Mukai Yutaka, Nureki Shin-ichi, Hata Masahiro, Shigenaga Takehiko, Tokimatsu Issei, Miyazaki Eishi, Kadota Jun-ichi, Yarita Kyoko, Kamei Katsuhiko
Аннотация
Exophiala dermatitidis pneumonia is extremely rare. Here we report a case of E. dermatitidis pneumonia successfully treated with long-term itraconazole therapy. A 63-year-old woman without a remarkable medical history developed a dry and chest pain. Chest radiographs revealed consolidation in the middle lobe of the lung. Cytologic examination by bronchoscopy showed filamentous fungi and E. dermatitidis was detected in the bronchoalveolar lavage fluid. After 5 months of itraconazole therapy, her symptoms improved and the area of consolidation diminished. Two weeks after discontinuing the itraconazole therapy, the area of consolidation reappeared. Itraconazole therapy was restarted and continued for 7 months. The abnormal shadow observed on the chest X-ray gradually diminished. Over a 27-month follow-up with periodic examination, there was no relapse and the patient had a favorable clinical course.