The Journal of asthma : official journal of the Association for the Care of Asthma · 2009
Serum vitamin A and beta-carotene levels in children with asthma.
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Al Senaidy Abdulrahman M
Аннотация
BACKGROUND: Low serum levels of dietary antioxidants are associated with allergic diseases including asthma. Vitamin A and carotenoids are dietary antioxidants that are likely to play an important role against airway inflammation.
METHODS: This study included 433 asthmatic schoolchildren and 537 healthy control subjects, between 6 and 18 years of age. Serum beta-carotene, vitamin A, cholesterol, and triglycerides levels were studied in all subjects.
RESULTS: Serum vitamin A concentration was significantly lower in asthmatic subjects than in healthy control subjects (19.4 +/- 1.1 mg/dL vs. 28.9 +/- 0.86 mg/dL) (p < 0.001). There were no significant differences in the levels of beta-carotene, cholesterol, and triglycerides between the two groups.
CONCLUSION: Reduction of vitamin A in asthmatic children may have etiological implications for the disease.
METHODS: This study included 433 asthmatic schoolchildren and 537 healthy control subjects, between 6 and 18 years of age. Serum beta-carotene, vitamin A, cholesterol, and triglycerides levels were studied in all subjects.
RESULTS: Serum vitamin A concentration was significantly lower in asthmatic subjects than in healthy control subjects (19.4 +/- 1.1 mg/dL vs. 28.9 +/- 0.86 mg/dL) (p < 0.001). There were no significant differences in the levels of beta-carotene, cholesterol, and triglycerides between the two groups.
CONCLUSION: Reduction of vitamin A in asthmatic children may have etiological implications for the disease.