Head & neck · 2025
Late Toxicity and Long-Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi-National Study.
СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Singer Susanne, Amdal Cecilie Delphin, Bjordal Kristin, Herlofson Bente Brokstad, Astrup Guro Lindviksmoen, Boehm Andreas, Wöhner Ulrike, Hammerlid Eva, Gama Ricardo Ribeiro, Jacinto Alexandre Arthur, Jansen Femke, Verdonck-de Leeuw Irma M, Dragan Tatiana, Duprez Fréderic, Kiyota Naomi, Pinto Monica, Krüger Maximilian, Guntinas-Lichius Orlando, Inhestern Johanna, Tramacere Francesco, Bonomo Pierluigi, Fanetti Giuseppe, Nuyts Sandra, Plath Michaela, Stempler Noa, Westgaard Kristine Løken, Taylor Katherine J
Аннотация
BACKGROUND: Because salivary gland cancers (SGC) are rare and include different tumor subtypes, data on their long-term quality of life and late toxicities are sparse.
METHODS: Multi-national study including SGC survivors more than 5 years after diagnosis. They completed the European Organisation for Research and Treatment of Cancer (EORTC) quality of life core questionnaire together with its head and neck cancer module and reported problems that were most bothering for them. Toxicity was clinically assessed.
RESULTS: Altogether, 60 survivors from nine countries participated and reported dry mouth (mean score 37.2), use of painkillers (35.0), problems with sexuality (30.1), insomnia (28.9), fatigue (27.8), trismus (24.9), and sticky saliva (23.3). The most frequently mentioned long-term problem was dry mouth, mentioned by a third of all participants. The most frequent toxicities were hearing impairment, soft tissue fibrosis, dry mouth, and cranial neuropathies.
CONCLUSIONS: Dry mouth is a frequent and disturbing problem in SGC survivors.
METHODS: Multi-national study including SGC survivors more than 5 years after diagnosis. They completed the European Organisation for Research and Treatment of Cancer (EORTC) quality of life core questionnaire together with its head and neck cancer module and reported problems that were most bothering for them. Toxicity was clinically assessed.
RESULTS: Altogether, 60 survivors from nine countries participated and reported dry mouth (mean score 37.2), use of painkillers (35.0), problems with sexuality (30.1), insomnia (28.9), fatigue (27.8), trismus (24.9), and sticky saliva (23.3). The most frequently mentioned long-term problem was dry mouth, mentioned by a third of all participants. The most frequent toxicities were hearing impairment, soft tissue fibrosis, dry mouth, and cranial neuropathies.
CONCLUSIONS: Dry mouth is a frequent and disturbing problem in SGC survivors.