Prehospital transfusion of allogeneic blood products.

PURPOSE OF REVIEW: The purpose of this article is to provide a structural and practical analysis of the currently available data concerning prehospital transfusion of allogeneic blood products in cases of trauma and severe bleeding.

RECENT FINDINGS: Prehospital transfusion of allogeneic blood products is a very early intervention, which may offer the potential to improve outcome, but that also comes with challenges including resource allocation, blood product storage, logistics, patient selection, legal and ethical considerations, adverse effects, and costs. Potential benefits including improved stability and reduction in coagulopathy and blood loss have not yet been clearly demonstrated.

SUMMARY: The questionable efficacy and challenges in clinical practice may outweigh the potential benefits of prehospital allogeneic transfusion.