Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) · 2025
[Secondary immunodeficiency of children with HIV: Clinical-epidemiological characteristics and factors associated with immunosuppression].
СтатьяНаблюдательное исследованиеАннотация на английскомНазвание и аннотация: Перевод пока не подготовлен
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Hernández-Morales María Del Rocío, Salgado-Valencia Juvenal, Mancilla-Hernández Eleazar, Espinosa-Texis Ana Maria, Papaqui-Limón Elizabeth, Alavez-López Estefanía, Castellanos-Guerrero Ana Karen
Аннотация
OBJETIVES: To determine the clinical and epidemiological characteristics and factors associated with immuno-suppression in children living with HIV.
METHODS: Observational, analytical, cross-sectional study of patients treated at the Outpatient Center for the Prevention and Care of AIDS and Sexually Transmitted Infections in the State of Puebla. Statistical analysis: percentages, frequencies, means, standard deviation and medians; Inferential analysis: X2 and univariate logistic regression. Statistical Package, for the Social Sciences 24.
RESULTS: A total of 83 patients aged 0 to 17 years (mean 7 years; SD ± 6.3) were selected, with an average age at diagnosis of 2.6 years. Vertical transmission was found in 90% of cases; women 47% and men 53%. The most frequent diseases were recurrent infections, lymphadenopathy, diarrhea; four cases of tuberculosis were reported, malnutrition 35%. Clinical category: N 25%, A 66%. Immunological category: 1-72%, 2-13%. Factors associated with immunosuppression were vertical transmission (p < 0.008) and CD4 level (p < 0.007).
CONCLUSIONS: Knowing the characteristics that describe pediatric HIV/AIDS, its clinical presentation, and its limitations, may guide to install improvements in care and follow-up, improving the prognosis of children.
METHODS: Observational, analytical, cross-sectional study of patients treated at the Outpatient Center for the Prevention and Care of AIDS and Sexually Transmitted Infections in the State of Puebla. Statistical analysis: percentages, frequencies, means, standard deviation and medians; Inferential analysis: X2 and univariate logistic regression. Statistical Package, for the Social Sciences 24.
RESULTS: A total of 83 patients aged 0 to 17 years (mean 7 years; SD ± 6.3) were selected, with an average age at diagnosis of 2.6 years. Vertical transmission was found in 90% of cases; women 47% and men 53%. The most frequent diseases were recurrent infections, lymphadenopathy, diarrhea; four cases of tuberculosis were reported, malnutrition 35%. Clinical category: N 25%, A 66%. Immunological category: 1-72%, 2-13%. Factors associated with immunosuppression were vertical transmission (p < 0.008) and CD4 level (p < 0.007).
CONCLUSIONS: Knowing the characteristics that describe pediatric HIV/AIDS, its clinical presentation, and its limitations, may guide to install improvements in care and follow-up, improving the prognosis of children.