Revista da Sociedade Brasileira de Medicina Tropical · 2017
Prevalence and antibiogram of methicillin resistant Staphylococcus aureus isolated from medical device-related infections; a retrospective study in Lahore, Pakistan.
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Sohail Muhammad, Latif Zakia
Аннотация
INTRODUCTION: With the advancement of medicine and surgery, various types of medical devices have become part of treatment strategies.
METHODS: Identification and antimicrobial sensitivity testing were done according to CLSI guidelines following standard microbiological practices.
RESULTS: Urinary catheter infections (31%) were most frequent followed by central venous catheter (18%) and orthopedic implants (15%). Methicillin resistant Staphylococcus aureus (MRSA) was a major cause of device-related infection after Escherichia coli (21%); other pathogens were Klebsiella pneumoniae (14%), Pseudomonas spp. (10%), Acinetobacter spp. (8%) and Candida species (7%). None of MRSA was resistant to vancomycin (MIC ≥16µg/mL). Resistance rates were 98% and 97% for ofloxacin and ciprofloxacin, respectively.
CONCLUSIONS: Escherichia coli and MRSA are major pathogens of medical device-related infections.
METHODS: Identification and antimicrobial sensitivity testing were done according to CLSI guidelines following standard microbiological practices.
RESULTS: Urinary catheter infections (31%) were most frequent followed by central venous catheter (18%) and orthopedic implants (15%). Methicillin resistant Staphylococcus aureus (MRSA) was a major cause of device-related infection after Escherichia coli (21%); other pathogens were Klebsiella pneumoniae (14%), Pseudomonas spp. (10%), Acinetobacter spp. (8%) and Candida species (7%). None of MRSA was resistant to vancomycin (MIC ≥16µg/mL). Resistance rates were 98% and 97% for ofloxacin and ciprofloxacin, respectively.
CONCLUSIONS: Escherichia coli and MRSA are major pathogens of medical device-related infections.
Предметные рубрики MeSH
AdolescentAdultAgedAged, 80 and overCandidaCatheter-Related InfectionsChildChild, PreschoolEquipment and SuppliesFemaleGram-Negative BacteriaHumansInfantInfant, NewbornMaleMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMiddle AgedPakistanPrevalenceProsthesis-Related InfectionsRetrospective StudiesRisk FactorsStaphylococcal InfectionsTime FactorsYoung Adult