Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2019
Gadolinium leakage in ocular structures in optic neuritis.
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Förster Alex, Böhme Johannes, Groden Christoph, Wenz Holger
Аннотация
BACKGROUND: We investigated the frequency of blood-retina barrier impairment in optic neuritis (ON) using gadolinium leakage in ocular structures (GLOS), a novel imaging marker on contrast enhanced fluid attenuated inversion recovery images (FLAIR).
METHODS: In 12 patients with acute ON who underwent repeated MRI the presence of GLOS was noted on contrast-enhanced FLAIR.
RESULTS: Bilateral GLOS was observed in 4 (33.3%): in 3 symmetrical, and in 1 asymmetrical. In the latter GLOS was ipsilateral to the ON.
CONCLUSIONS: GLOS may be observed frequently in ON. Asymmetrical GLOS may be caused by a more local effect of ON.
METHODS: In 12 patients with acute ON who underwent repeated MRI the presence of GLOS was noted on contrast-enhanced FLAIR.
RESULTS: Bilateral GLOS was observed in 4 (33.3%): in 3 symmetrical, and in 1 asymmetrical. In the latter GLOS was ipsilateral to the ON.
CONCLUSIONS: GLOS may be observed frequently in ON. Asymmetrical GLOS may be caused by a more local effect of ON.