A patient with concurrent multiple sclerosis and moyamoya disease.

BACKGROUND

Moyamoya disease (MMD) is a rare vasculopathy and Multiple Sclerosis (MS) is an autoimmune disease which causes CNS demyelination. While most literature has focused on misdiagnosis of MMD as an "MS-mimic", we present a patient in which both co-existed.

METHODS

Case Report

RESULTS

A 57-year-old woman presented with gait dysfunction and paresthesias in both feet. MRI revealed brain and spinal cord lesions consistent with MS. Vessel imaging revealed multivessel stenosis consistent with MMD. Lumbar puncture demonstrated oligoclonal bands, leading to two diagnoses, MS and MMD.

CONCLUSIONS

MS can exist concurrently with MMD, potentially due to underlying propensity for autoimmunity.