Precocious Puberty in Boys: A Study Based on Five Years of Data from a Single Center in Northern China.

OBJECTIVE

To evaluate the clinical features and etiology of precocious puberty (PP) in Chinese boys.

METHODS

In this study, data from boys who were referred for evaluation of PP from 2015 to 2020 at a tertiary hospital in Northern China were retrospectively analyzed.

RESULTS

Eighty-two boys were diagnosed with PP from 2015 to 2020. Sixty-two patients (75.6%) were diagnosed with central PP (CPP), and twenty patients (24.4%) were diagnosed with peripheral PP (PPP). In the CPP group, forty-nine cases were classified as idiopathic CPP, and thirteen patients had pathogenic CPP. The top three causes of PPP were congenital adrenal hyperplasia, germ cell tumors and familial male-limited PP.

CONCLUSION

The etiology of PP in males is diverse. The majority of CPP cases in Chinese boys are idiopathic rather than organic.