Медицинская библиотека · Science (New York, N.Y.) · 2021
Daily energy expenditure through the human life course.
Pontzer Herman, Yamada Yosuke, Sagayama Hiroyuki, Ainslie Philip N, Andersen Lene F, Anderson Liam J, Arab Lenore, Baddou Issaad, Bedu-Addo Kweku, Blaak Ellen E, Blanc Stephane, Bonomi Alberto G, Bouten Carlijn V C, Bovet Pascal, Buchowski Maciej S, Butte Nancy F, Camps Stefan G, Close Graeme L, Cooper Jamie A, Cooper Richard, Das Sai Krupa, Dugas Lara R, Ekelund Ulf, Entringer Sonja, Forrester Terrence, Fudge Barry W, Goris Annelies H, Gurven Michael, Hambly Catherine, El Hamdouchi Asmaa, Hoos Marjije B, Hu Sumei, Joonas Noorjehan, Joosen Annemiek M, Katzmarzyk Peter, Kempen Kitty P, Kimura Misaka, Kraus William E, Kushner Robert F, Lambert Estelle V, Leonard William R, Lessan Nader, Martin Corby, Medin Anine C, Meijer Erwin P, Morehen James C, Morton James P, Neuhouser Marian L, Nicklas Teresa A, Ojiambo Robert M, Pietiläinen Kirsi H, Pitsiladis Yannis P, Plange-Rhule Jacob, Plasqui Guy, Prentice Ross L, Rabinovich Roberto A, Racette Susan B, Raichlen David A, Ravussin Eric, Reynolds Rebecca M, Roberts Susan B, Schuit Albertine J, Sjödin Anders M, Stice Eric, Urlacher Samuel S, Valenti Giulio, Van Etten Ludo M, Van Mil Edgar A, Wells Jonathan C K, Wilson George, Wood Brian M, Yanovski Jack, Yoshida Tsukasa, Zhang Xueying, Murphy-Alford Alexia J, Loechl Cornelia, Luke Amy H, Rood Jennifer, Schoeller Dale A, Westerterp Klaas R, Wong William W, Speakman John R, IAEA DLW Database Consortium
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Аннотация
Total daily energy expenditure ("total expenditure") reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass-adjusted expenditure accelerates rapidly in neonates to ~50% above adult values at ~1 year; declines slowly to adult levels by ~20 years; remains stable in adulthood (20 to 60 years), even during pregnancy; then declines in older adults. These changes shed light on human development and aging and should help shape nutrition and health strategies across the life span.
Для цитирования: Pontzer Herman, Yamada Yosuke, Sagayama Hiroyuki, Ainslie Philip N, Andersen Lene F, Anderson Liam J, Arab Lenore, Baddou Issaad, Bedu-Addo Kweku, Blaak Ellen E, Blanc Stephane, Bonomi Alberto G, Bouten Carlijn V C, Bovet Pascal, Buchowski Maciej S, Butte Nancy F, Camps Stefan G, Close Graeme L, Cooper Jamie A, Cooper Richard, Das Sai Krupa, Dugas Lara R, Ekelund Ulf, Entringer Sonja, Forrester Terrence, Fudge Barry W, Goris Annelies H, Gurven Michael, Hambly Catherine, El Hamdouchi Asmaa, Hoos Marjije B, Hu Sumei, Joonas Noorjehan, Joosen Annemiek M, Katzmarzyk Peter, Kempen Kitty P, Kimura Misaka, Kraus William E, Kushner Robert F, Lambert Estelle V, Leonard William R, Lessan Nader, Martin Corby, Medin Anine C, Meijer Erwin P, Morehen James C, Morton James P, Neuhouser Marian L, Nicklas Teresa A, Ojiambo Robert M, Pietiläinen Kirsi H, Pitsiladis Yannis P, Plange-Rhule Jacob, Plasqui Guy, Prentice Ross L, Rabinovich Roberto A, Racette Susan B, Raichlen David A, Ravussin Eric, Reynolds Rebecca M, Roberts Susan B, Schuit Albertine J, Sjödin Anders M, Stice Eric, Urlacher Samuel S, Valenti Giulio, Van Etten Ludo M, Van Mil Edgar A, Wells Jonathan C K, Wilson George, Wood Brian M, Yanovski Jack, Yoshida Tsukasa, Zhang Xueying, Murphy-Alford Alexia J, Loechl Cornelia, Luke Amy H, Rood Jennifer, Schoeller Dale A, Westerterp Klaas R, Wong William W, Speakman John R, IAEA DLW Database Consortium. Daily energy expenditure through the human life course.. Science (New York, N.Y.). 2021. DOI: 10.1126/science.abe5017.
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