Mood disorders in the medically ill: scientific review and recommendations.
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Ошибки и ограничения
История · было → стало
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Evans Dwight L, Charney Dennis S, Lewis Lydia, Golden Robert N, Gorman Jack M, Krishnan K Ranga Rama, Nemeroff Charles B, Bremner J Douglas, Carney Robert M, Coyne James C, Delong Mahlon R, Frasure-Smith Nancy, Glassman Alexander H, Gold Philip W, Grant Igor, Gwyther Lisa, Ironson Gail, Johnson Robert L, Kanner Andres M, Katon Wayne J, Kaufmann Peter G, Keefe Francis J, Ketter Terence, Laughren Thomas P, Leserman Jane, Lyketsos Constantine G, McDonald William M, McEwen Bruce S, Miller Andrew H, Musselman Dominique, O'Connor Christopher, Petitto John M, Pollock Bruce G, Robinson Robert G, Roose Steven P, Rowland Julia, Sheline Yvette, Sheps David S, Simon Gregory, Spiegel David, Stunkard Albert, Sunderland Trey, Tibbits Paul, Valvo William J
Аннотация
DATA SOURCES: Data were culled from the 2002 Depression and Bipolar Support Alliance Conference proceedings and a literature review addressing prevalence, risk factors, diagnosis, and treatment. This review also considered the experience of primary and specialty care providers, policy analysts, and patient advocates. The review and recommendations reflect the expert opinion of the authors.
STUDY SELECTION/DATA EXTRACTION: Reviews of epidemiology and mechanistic studies were included, as were open-label and randomized, controlled trials on treatment of depression in patients with medical comorbidities. Data on study design, population, and results were extracted for review of evidence that includes tables of prevalence and pharmacological treatment. The effect of depression and bipolar disorder on selected medical comorbidities was assessed, and recommendations for practice, research, and policy were developed.
CONCLUSIONS: A growing body of evidence suggests that biological mechanisms underlie a bidirectional link between mood disorders and many medical illnesses. In addition, there is evidence to suggest that mood disorders affect the course of medical illnesses. Further prospective studies are warranted.