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Nature communications · 2017

Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод пока не подготовлен
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Adema Coen M, Hillier LaDeana W, Jones Catherine S, Loker Eric S, Knight Matty, Minx Patrick, Oliveira Guilherme, Raghavan Nithya, Shedlock Andrew, do Amaral Laurence Rodrigues, Arican-Goktas Halime D, Assis Juliana G, Baba Elio Hideo, Baron Olga L, Bayne Christopher J, Bickham-Wright Utibe, Biggar Kyle K, Blouin Michael, Bonning Bryony C, Botka Chris, Bridger Joanna M, Buckley Katherine M, Buddenborg Sarah K, Lima Caldeira Roberta, Carleton Julia, Carvalho Omar S, Castillo Maria G, Chalmers Iain W, Christensens Mikkel, Clifton Sandra, Cosseau Celine, Coustau Christine, Cripps Richard M, Cuesta-Astroz Yesid, Cummins Scott F, di Stephano Leon, Dinguirard Nathalie, Duval David, Emrich Scott, Feschotte Cédric, Feyereisen Rene, FitzGerald Peter, Fronick Catrina, Fulton Lucinda, Galinier Richard, Gava Sandra G, Geusz Michael, Geyer Kathrin K, Giraldo-Calderón Gloria I, de Souza Gomes Matheus, Gordy Michelle A, Gourbal Benjamin, Grunau Christoph, Hanington Patrick C, Hoffmann Karl F, Hughes Daniel, Humphries Judith, Jackson Daniel J, Jannotti-Passos Liana K, de Jesus Jeremias Wander, Jobling Susan, Kamel Bishoy, Kapusta Aurélie, Kaur Satwant, Koene Joris M, Kohn Andrea B, Lawson Dan, Lawton Scott P, Liang Di, Limpanont Yanin, Liu Sijun, Lockyer Anne E, Lovato TyAnna L, Ludolf Fernanda, Magrini Vince, McManus Donald P, Medina Monica, Misra Milind, Mitta Guillaume, Mkoji Gerald M, Montague Michael J, Montelongo Cesar, Moroz Leonid L, Munoz-Torres Monica C, Niazi Umar, Noble Leslie R, Oliveira Francislon S, Pais Fabiano S, Papenfuss Anthony T, Peace Rob, Pena Janeth J, Pila Emmanuel A, Quelais Titouan, Raney Brian J, Rast Jonathan P, Rollinson David, Rosse Izinara C, Rotgans Bronwyn, Routledge Edwin J, Ryan Kathryn M, Scholte Larissa L S, Storey Kenneth B, Swain Martin, Tennessen Jacob A, Tomlinson Chad, Trujillo Damian L, Volpi Emanuela V, Walker Anthony J, Wang Tianfang, Wannaporn Ittiprasert, Warren Wesley C, Wu Xiao-Jun, Yoshino Timothy P, Yusuf Mohammed, Zhang Si-Ming, Zhao Min, Wilson Richard K

Аннотация

Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты