Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
The Impact of Mandated Universal Screening for Congenital Cytomegalovirus: The Minnesota Experience.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Holden Lily, Carlson Anisa M, Jayawardena Asitha, Meyer Abby, Roby Brianne, Lunos Scott, Novak Jessica, Rabusch Stacey, Redmann Andrew J
Аннотация
OBJECTIVE: To investigate trends in evaluation and management of patients with cCMV at a major pediatric center following the institution of universal cCMV screening.
STUDY DESIGN: Retrospective cohort study.
SETTING: Tertiary academic hospital.
METHODS: Patients <18 years with a diagnosis of cCMV between January 2021 and February 2024 were examined. Three cohorts were analyzed: 2021 and earlier (before screening guidelines), 2022 (screening recommended but not mandated), and 2023 and later (universal screening). Patient charts were reviewed for workup and treatment of cCMV.
RESULTS: 132 patients met criteria. There was a significant difference in age at first audiology visit following cCMV diagnosis between cohorts 1 (0.71 ± 1.8), 2 (0.26 ± 0.23), and 3 (0.07 ± 0.06) (P = .02). There was a significant increase in the absolute number of mild hearing loss diagnoses in 2023 and later compared to 2022 (8 and 2, P < .01), but no difference in severe to profound hearing loss diagnoses between the cohorts (5 and 3, P = .2). Between cohorts 2 and 3, there were increases in the absolute number of patients undergoing ID consultation (11 vs 24), ENT consultation (9 vs 22), and treatment with antiviral therapy (7 vs 9) (P < .01).
CONCLUSIONS: Universal cCMV screening decreased the age at first audiology visit following cCMV diagnosis. Universal screening increased the number of diagnoses of mild hearing loss. The number of patients undergoing workup for cCMV also increased. Additional research is needed to assess the long-term audiologic outcomes and benefits of universal screening.
STUDY DESIGN: Retrospective cohort study.
SETTING: Tertiary academic hospital.
METHODS: Patients <18 years with a diagnosis of cCMV between January 2021 and February 2024 were examined. Three cohorts were analyzed: 2021 and earlier (before screening guidelines), 2022 (screening recommended but not mandated), and 2023 and later (universal screening). Patient charts were reviewed for workup and treatment of cCMV.
RESULTS: 132 patients met criteria. There was a significant difference in age at first audiology visit following cCMV diagnosis between cohorts 1 (0.71 ± 1.8), 2 (0.26 ± 0.23), and 3 (0.07 ± 0.06) (P = .02). There was a significant increase in the absolute number of mild hearing loss diagnoses in 2023 and later compared to 2022 (8 and 2, P < .01), but no difference in severe to profound hearing loss diagnoses between the cohorts (5 and 3, P = .2). Between cohorts 2 and 3, there were increases in the absolute number of patients undergoing ID consultation (11 vs 24), ENT consultation (9 vs 22), and treatment with antiviral therapy (7 vs 9) (P < .01).
CONCLUSIONS: Universal cCMV screening decreased the age at first audiology visit following cCMV diagnosis. Universal screening increased the number of diagnoses of mild hearing loss. The number of patients undergoing workup for cCMV also increased. Additional research is needed to assess the long-term audiologic outcomes and benefits of universal screening.