Abnormal electroencephalographic rhythms from quiet wakefulness to light sleep in Alzheimer's disease patients with mild cognitive impairment.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Salamone Enrico Michele, Carpi Matteo, Noce Giuseppe, Del Percio Claudio, Lopez Susanna, Lizio Roberta, Jakhar Dharmendra, Eldellaa Ali, Isaza Veronica Henao, Bölükbaş Burcu, Soricelli Andrea, Salvatore Marco, Güntekin Bahar, Yener Görsev, Massa Federico, Arnaldi Dario, Famà Francesco, Pardini Matteo, Ferri Raffaele, Salemi Michele, Lanuzza Bartolo, Stocchi Fabrizio, Vacca Laura, Coletti Chiara, Marizzoni Moira, Taylor John Paul, Hanoğlu Lutfu, Yılmaz Nesrin Helvacı, Kıyı İlayda, Kula Hilal, Frisoni Giovanni B, Cuoco Sofia, Barone Paolo, D'Anselmo Anita, Bonanni Laura, Biundo Roberta, D'Antonio Fabrizia, Bruno Giuseppe, Giubilei Franco, Antonini Angelo, Babiloni Claudio
Аннотация
METHODS: Datasets of 34 ADMCI and 22 matched healthy elderly (Nold) subjects were obtained from international archives. EEG recordings lasted approximately 30 min. Transitions of EEG activity from quiet wakefulness (alpha-dominant) to light sleep (theta-dominant ripples) were scored according to Hori's vigilance stages. Cortical source activities were computed using the eLORETA software.
RESULTS: ADMCI (t-ADMCI, N = 18) over Nold (t-Nold, N = 11) participants were characterized by greater frontal EEG delta source activities and a lesser reduction (reactivity) in the posterior alpha source activities from quiet wakefulness to ripples. Notably, EEG delta source activities during quiet wakefulness were also greater in the ADMCI group transitioning to light sleep as compared to patients without said vigilance reduction.
CONCLUSIONS: These results suggest that ADMCI patients with a greater susceptibility to daytime sleepiness may show characteristic EEG delta and alpha rhythms in the transition from quiet vigilance to daytime sleep.
SIGNIFICANCE: Our study showed a derangement of EEG rhythms during the transition to sleep possibly specific to AD.