Endocrinology and metabolism (Seoul, Korea) · 2020
Diagnosis and Treatment of Growth Hormone Deficiency: A Position Statement from Korean Endocrine Society and Korean Society of Pediatric Endocrinology.
СтатьяПоддержка исследования: вне правительства СШАConsensus StatementНазвание и аннотация: Перевод пока не подготовлен
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Kim Jung Hee, Chae Hyun Wook, Chin Sang Ouk, Ku Cheol Ryong, Park Kyeong Hye, Lim Dong Jun, Kim Kwang Joon, Lim Jung Soo, Kim Gyuri, Choi Yun Mi, Ahn Seong Hee, Jeon Min Ji, Hwangbo Yul, Lee Ju Hee, Kim Bu Kyung, Choi Yong Jun, Lee Kyung Ae, Moon Seong-Su, Ahn Hwa Young, Choi Hoon Sung, Hong Sang Mo, Shin Dong Yeob, Seo Ji A, Kim Se Hwa, Oh Seungjoon, Yu Sung Hoon, Kim Byung Joon, Shin Choong Ho, Kim Sung-Woon, Kim Chong Hwa, Lee Eun Jig
Аннотация
Growth hormone (GH) deficiency is caused by congenital or acquired causes and occurs in childhood or adulthood. GH replacement therapy brings benefits to body composition, exercise capacity, skeletal health, cardiovascular outcomes, and quality of life. Before initiating GH replacement, GH deficiency should be confirmed through proper stimulation tests, and in cases with proven genetic causes or structural lesions, repeated GH stimulation testing is not necessary. The dosing regimen of GH replacement therapy should be individualized, with the goal of minimizing side effects and maximizing clinical improvements. The Korean Endocrine Society and the Korean Society of Pediatric Endocrinology have developed a position statement on the diagnosis and treatment of GH deficiency. This position statement is based on a systematic review of evidence and expert opinions.