Cancer · 1994
Gliomas in patients with acquired immune deficiency syndrome.
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Chamberlain M C
Аннотация
BACKGROUND: Ten percent of patients with acquired immune deficiency syndrome (AIDS) have intracerebral mass lesions of which the majority are due either to toxoplasmosis or primary central nervous system lymphomas.
METHODS: Three patients with AIDS presented with solitary intracerebral mass lesions and were found by pathologic examination to have gliomas.
RESULTS: After surgery, all patients were treated with radiotherapy and procarbazine, comustine, and vincristine multiagent chemotherapy. Median follow-up is 12 months.
CONCLUSIONS: Occasionally, patients with AIDS and intracerebral mass lesions have primary nonlymphomatous brain tumors, an occurrence not related clearly to underlying immunoincompetence.
METHODS: Three patients with AIDS presented with solitary intracerebral mass lesions and were found by pathologic examination to have gliomas.
RESULTS: After surgery, all patients were treated with radiotherapy and procarbazine, comustine, and vincristine multiagent chemotherapy. Median follow-up is 12 months.
CONCLUSIONS: Occasionally, patients with AIDS and intracerebral mass lesions have primary nonlymphomatous brain tumors, an occurrence not related clearly to underlying immunoincompetence.