Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2020
Vitamin D: association with eosinophil counts and IgE levels in children with asthma.
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Amorim Claudio Luiz Castro Gomes de, Oliveira Joice Mara de, Rodrigues Antenor, Furlanetto Karina Couto, Pitta Fabio
Аннотация
In this cross-sectional study, we investigated the relationship that levels of vitamin D had with eosinophil counts and IgE levels in 26 children with asthma (6-12 years of age) in the city of Londrina, Brazil. Vitamin D levels were found to correlate significantly, albeit moderately, with age (r = -0.51) and eosinophilia (r = -0.49), although not with IgE levels (r = -0.12). When we stratified the sample into two groups by the median vitamin D level (< or ≥ 24 ng/mL), we found that those in the < 24 ng/mL group were older, had higher eosinophil counts, and had higher IgE levels. To our knowledge, this is the first study to show an association between low levels of vitamin D and more pronounced eosinophilia in children with asthma in Brazil.