Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2024
Predictive Ability of the Academic Research Consortium High Bleeding Risk Criteria in Patients Undergoing Percutaneous Coronary Intervention According to Body Mass Index.
СтатьяСравнительное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gao Michael, Spirito Alessandro, Sartori Samantha, Vogel Birgit, Gitto Mauro, Oliva Angelo, Smith Kenneth F, Sweeny Joseph, Krishnan Prakash, Moreno Pedro, Krishnamoorthy Parasuram Melarcode, Kini Annapoorna, Dangas George, Sharma Samin K, Mehran Roxana
Аннотация
BACKGROUND: Whether the high bleeding risk (HBR) criteria of the Academic Research Consortium (ARC) have a consistent predictive ability across different categories of body mass index (BMI) remains unclear.
METHODS: Consecutive patients undergoing percutaneous coronary intervention (PCI) between 2012 and 2019 at Mount Sinai Hospital (New York, USA) were stratified into five BMI categories (18.5-24.9 kg/m2 [normoweight], 25-29.9 kg/m2 [overweight], 30-34.9 kg/m2 [Class I obesity], 35-39.9 kg/m2 [Class II obesity], and BMI ≥ 40 kg/m2 [Class III obesity]) and by HBR status. The primary outcome was major bleeding at 1 year after PCI.
RESULTS: Among 16,123 patients, normoweight, overweight, class I, class II, and class III obesity were found in 23.7%, 41%, 24.5%, 9.3%, 4.8% of patients, respectively. Fulfillment of the ARC-HBR criteria ranged between 34.4% and 48.5% across these BMI categories. One-year rates of major bleeding was 6% in normoweight patients (reference), 4.1% in overweight (adj.HR 0.73, 95% CI 0.60-0.88), 3.5% in class I (adj.HR 0.62, 95% CI 0.49-0.77), 4.2% in class II (adj.HR 0.72, 95% CI 0.54-0.96), and 4.9% in class III (adj.HR 0.83, 95% CI 0.58-1.18) obesity. Consistently across the 5 BMI categories, the fulfillment of ARC-HBR criteria was related with > 4% rates of major bleeding at 1-year and with ≥ 2 times risk increase of major bleeding (pint = 0.177).
CONCLUSIONS: The presence of the ARC-HBR criteria predicted a significantly increased risk of major bleeding consistently in each BMI category.
METHODS: Consecutive patients undergoing percutaneous coronary intervention (PCI) between 2012 and 2019 at Mount Sinai Hospital (New York, USA) were stratified into five BMI categories (18.5-24.9 kg/m2 [normoweight], 25-29.9 kg/m2 [overweight], 30-34.9 kg/m2 [Class I obesity], 35-39.9 kg/m2 [Class II obesity], and BMI ≥ 40 kg/m2 [Class III obesity]) and by HBR status. The primary outcome was major bleeding at 1 year after PCI.
RESULTS: Among 16,123 patients, normoweight, overweight, class I, class II, and class III obesity were found in 23.7%, 41%, 24.5%, 9.3%, 4.8% of patients, respectively. Fulfillment of the ARC-HBR criteria ranged between 34.4% and 48.5% across these BMI categories. One-year rates of major bleeding was 6% in normoweight patients (reference), 4.1% in overweight (adj.HR 0.73, 95% CI 0.60-0.88), 3.5% in class I (adj.HR 0.62, 95% CI 0.49-0.77), 4.2% in class II (adj.HR 0.72, 95% CI 0.54-0.96), and 4.9% in class III (adj.HR 0.83, 95% CI 0.58-1.18) obesity. Consistently across the 5 BMI categories, the fulfillment of ARC-HBR criteria was related with > 4% rates of major bleeding at 1-year and with ≥ 2 times risk increase of major bleeding (pint = 0.177).
CONCLUSIONS: The presence of the ARC-HBR criteria predicted a significantly increased risk of major bleeding consistently in each BMI category.