Comparative predictive value of anthropometric indexes for hypertension: a 15-year prospective cohort study.

UNLABELLED: Background The objective of this study was to ascertain whether cardiometabolic index(CMI), visceral adiposity index (VAI), dysfunctional adiposity index (DAI), and body adiposity index (BAI) are superior predictors of future hypertension risk when compared with conventional indicators such as waist circumference(WC), body mass index (BMI) and waist-to-height ratio(WHtR).

MATERIAL AND

METHODS

This is a post hoc analysis of the MONICA protocol. We selected 597 patients based on inclusions criteria. Data collection began in 1992, and follow-up was conducted on the same group of participants in 2007. The study collected anthropometric indexes and biochemical data.

RESULTS

After adjusting for confounding factors using multivariate Cox regression analysis, the following results were observed: CMI [HR: 1.754 (1.240-2.480); P = 0.001], VAI [HR: 1.533 (1.074-2.187); P = 0.018], DAI [HR: 1.382 (0.982-1.945); P = 0.064], BAI [HR: 2.791 (1.790-4.352); P < 0.001], WC [HR: 2.234 (1.510-3.307); P < 0.001], WHtR [HR: 2.303 (1.589-3.339); P < 0.001], and BMI [HR: 2.488 (1.778-3.561); P < 0.001] were all significantly associated with the incidence of hypertension. ROC curve analysis showed that the area under the curve (AUC) for WC product was the highest (0.649, 95% CI: 0.605-0.693), followed by BMI (0.648, 95% CI: 0.603-0.692), WHtR (0.646, 95% CI: 0.601-0.690), and then by CMI (0.603, 95% CI: 0.557-0.649).

CONCLUSIONS

Although the CMI, VAI, DAI and BAI can all be utilised as independent predictors of hypertension, the predictive discriminatory power of these novel indicators for hypertension remains inferior to that of traditional indicators such as WC, BMI and WHtR.