Non-mumps Viral Parotitis During the 2014-2015 Influenza Season in the United States.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Elbadawi Lina I, Talley Pamela, Rolfes Melissa A, Millman Alexander J, Reisdorf Erik, Kramer Natalie A, Barnes John R, Blanton Lenee, Christensen Jaime, Cole Stefanie, Danz Tonya, Dreisig John J, Garten Rebecca, Haupt Thomas, Isaac Beth M, Jackson Mary Anne, Kocharian Anna, Leifer Daniel, Martin Karen, McHugh Lisa, McNall Rebecca J, Palm Jennifer, Radford Kay W, Robinson Sara, Rosen Jennifer B, Sakthivel Senthilkumar K, Shult Peter, Strain Anna K, Turabelidze George, Webber Lori A, Weinberg Meghan Pearce, Wentworth David E, Whitaker Brett L, Finelli Lyn, Jhung Michael A, Lynfield Ruth, Davis Jeffrey P
Аннотация
METHODS: NMP was defined as acute parotitis or other salivary gland swelling of >2 days duration in a person with a mumps- negative laboratory result. Using a standardized questionnaire, we collected demographic and clinical information. Buccal samples were tested at the CDC for selected viruses, including mumps, influenza, human parainfluenza viruses (HPIVs) 1-4, adenoviruses, cytomegalovirus, Epstein-Barr virus (EBV), herpes simplex viruses (HSVs) 1 and 2, and human herpes viruses (HHVs) 6A and 6B.
RESULTS: Among the 320 patients, 65% were male, median age was 14.5 years (range, 0-90), and 67% reported unilateral parotitis. Commonly reported symptoms included sore throat (55%) and fever (48%). Viruses were detected in 210 (71%) of 294 NMP patients with adequate samples for testing, ≥2 viruses were detected in 37 samples, and 248 total virus detections were made among all samples. These included 156 influenza A(H3N2), 42 HHV6B, 32 EBV, 8 HPIV2, 2 HPIV3, 3 adenovirus, 4 HSV-1, and 1 HSV-2. Influenza A(H3N2), HHV6B, and EBV were the most frequently codetected viruses.
CONCLUSIONS: Our findings suggest that, in addition to mumps, clinicians should consider respiratory viral (influenza) and herpes viral etiologies for parotitis, particularly among patients without epidemiologic links to mumps cases or outbreaks.