Environmental research · 2025
Sand and dust storms exacerbate the toxicity of particle pollution on mortality: A cohort study among 1.5 million Chinese older adults.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Guo Chenghua, Wu Jingyi, Zhang Weidong, Fang Shanzhen, Li Pengfei, Zhang Luxia
Аннотация
OBJECTIVE: The impact of desert-originated dust has been underestimated in fine particulate matters (PM2.5)-related disease burden studies. This study aimed to assess the association of long-term dust PM2.5 exposure and all-cause mortality among older adults in China.
METHODS: A cohort study using electronic health records (2010-2020) across Weinan, a city in northwest China, which experiences persistently high PM2.5 levels and frequent sand and dust storms, included 1,553,724 adults aged ≥45 years. Annual average dust and non-dust PM2.5 exposures were matched for each participant based on their residential locations. Cox regression models were used to estimate mortality risks associated with long-term exposure to both PM2.5 sources. A tensor product interaction function was applied to develop a two-dimensional joint exposure-response function linking mortality to both dust and non-dust PM2.5 exposures to quantify the burden of deaths attributable to PM2.5 sources.
RESULTS: During 8,951,372 person-years of follow-up, 45,273 deaths (2.91 %) occurred. Three-year average exposure to dust and non-dust PM2.5 were 14.85 and 36.78 μg/m3, respectively. Each 1 μg/m3 increase in dust PM2.5 was associated with a 29.0 % (95 % confidence interval [CI]: 28.3, 29.8 %) increase in mortality risk among older adults, versus 13.4 % (95 % CI: 13.1, 13.7 %) for non-dust PM2.5. While dust PM2.5 constituted only 25.9 % of total PM2.5 exposure, it contributed 40.1 % of PM2.5-related deaths in 2019.
CONCLUSION: Dust PM2.5 has a stronger adverse association with mortality among older adults than non-dust PM2.5. These findings provide critical insights into PM2.5 source-specific health impacts, informing targeted air pollution control strategies and public health interventions.
METHODS: A cohort study using electronic health records (2010-2020) across Weinan, a city in northwest China, which experiences persistently high PM2.5 levels and frequent sand and dust storms, included 1,553,724 adults aged ≥45 years. Annual average dust and non-dust PM2.5 exposures were matched for each participant based on their residential locations. Cox regression models were used to estimate mortality risks associated with long-term exposure to both PM2.5 sources. A tensor product interaction function was applied to develop a two-dimensional joint exposure-response function linking mortality to both dust and non-dust PM2.5 exposures to quantify the burden of deaths attributable to PM2.5 sources.
RESULTS: During 8,951,372 person-years of follow-up, 45,273 deaths (2.91 %) occurred. Three-year average exposure to dust and non-dust PM2.5 were 14.85 and 36.78 μg/m3, respectively. Each 1 μg/m3 increase in dust PM2.5 was associated with a 29.0 % (95 % confidence interval [CI]: 28.3, 29.8 %) increase in mortality risk among older adults, versus 13.4 % (95 % CI: 13.1, 13.7 %) for non-dust PM2.5. While dust PM2.5 constituted only 25.9 % of total PM2.5 exposure, it contributed 40.1 % of PM2.5-related deaths in 2019.
CONCLUSION: Dust PM2.5 has a stronger adverse association with mortality among older adults than non-dust PM2.5. These findings provide critical insights into PM2.5 source-specific health impacts, informing targeted air pollution control strategies and public health interventions.