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Войти в исследования Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials · 2010
[Study on in vitro release and transdermal behaviors of mumps cataplasm of complex prescription].
Аннотация на английскомСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Song Jin-yan, Guo Zeng-jun, Zheng Na, Wu Nan, Mao Jun-jun, Pang Xiao-ming
Аннотация
OBJECTIVE: To investigate the in vitro release and transdermal behaviors of mumps cataplasm of complex prescription.
METHODS: The improved Franz difficusion was used and the concentration of drugs was detected. DCS was determined by HPLC and flavanoid contents were determined by UV.
RESULTS: The accumulation skin permeation percentage of DCS and flavanoid was 32% and 21%, respectively, the in vitro release percentage of DCS and flavanoid was 47% and 42%, respectively.
CONCLUSION: The transdermal behavior of mumps cataplasm of complex prescription is an zero-order kinetics progress. The in vitro release behavior is in accordance with the Higuchi equation.
METHODS: The improved Franz difficusion was used and the concentration of drugs was detected. DCS was determined by HPLC and flavanoid contents were determined by UV.
RESULTS: The accumulation skin permeation percentage of DCS and flavanoid was 32% and 21%, respectively, the in vitro release percentage of DCS and flavanoid was 47% and 42%, respectively.
CONCLUSION: The transdermal behavior of mumps cataplasm of complex prescription is an zero-order kinetics progress. The in vitro release behavior is in accordance with the Higuchi equation.