[Lipid peroxidation in patients with epidemic parotitis complicated by pancreatitis].

The serum concentrations of diene conjugates (DC) and malonic dialdehyde (MDA) were measured in patients with epidemic parotitis (EP) complicated or not complicated by acute pancreatitis (AP). Forty-eight patients with EP were examined. Group 1 consisted of 30 patients with EP complicated by AP; Group 2 consisted of 18 patients with non-complicated EP. The serum samples from 21 healthy donors were used as controls. DC and MDA concentrations were measured after first clinical signs of AP (days 5th to 8th) appeared and before discharge. Serum samples from patients without AP were taken also on days 5th to 8th and before discharge. Lipid peroxidation (LP) proved to be activated in patients with EP, and in patients with complicated EP the increase in the concentration of primary LP products (DC) and intermediate (MDA) LP products was greater.