Alzheimer's & dementia : the journal of the Alzheimer's Association · 2020

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia.

СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен

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Kivipelto Miia, Mangialasche Francesca, Snyder Heather M, Allegri Ricardo, Andrieu Sandrine, Arai Hidenori, Baker Laura, Belleville Sylvie, Brodaty Henry, Brucki Sonia M, Calandri Ismael, Caramelli Paulo, Chen Christopher, Chertkow Howard, Chew Effie, Choi Seong H, Chowdhary Neerja, Crivelli Lucía, Torre Rafael De La, Du Yifeng, Dua Tarun, Espeland Mark, Feldman Howard H, Hartmanis Maris, Hartmann Tobias, Heffernan Megan, Henry Christiani J, Hong Chang H, Håkansson Krister, Iwatsubo Takeshi, Jeong Jee H, Jimenez-Maggiora Gustavo, Koo Edward H, Launer Lenore J, Lehtisalo Jenni, Lopera Francisco, Martínez-Lage Pablo, Martins Ralph, Middleton Lefkos, Molinuevo José L, Montero-Odasso Manuel, Moon So Y, Morales-Pérez Kristal, Nitrini Ricardo, Nygaard Haakon B, Park Yoo K, Peltonen Markku, Qiu Chengxuan, Quiroz Yakeel T, Raman Rema, Rao Naren, Ravindranath Vijayalakshmi, Rosenberg Anna, Sakurai Takashi, Salinas Rosa M, Scheltens Philip, Sevlever Gustavo, Soininen Hilkka, Sosa Ana L, Suemoto Claudia K, Tainta-Cuezva Mikel, Velilla Lina, Wang Yongxiang, Whitmer Rachel, Xu Xin, Bain Lisa J, Solomon Alina, Ngandu Tiia, Carrillo Maria C

Аннотация

Reducing the risk of dementia can halt the worldwide increase of affected people. The multifactorial and heterogeneous nature of late-onset dementia, including Alzheimer's disease (AD), indicates a potential impact of multidomain lifestyle interventions on risk reduction. The positive results of the landmark multidomain Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) support such an approach. The World-Wide FINGERS (WW-FINGERS), launched in 2017 and including over 25 countries, is the first global network of multidomain lifestyle intervention trials for dementia risk reduction and prevention. WW-FINGERS aims to adapt, test, and optimize the FINGER model to reduce risk across the spectrum of cognitive decline-from at-risk asymptomatic states to early symptomatic stages-in different geographical, cultural, and economic settings. WW-FINGERS aims to harmonize and adapt multidomain interventions across various countries and settings, to facilitate data sharing and analysis across studies, and to promote international joint initiatives to identify globally implementable and effective preventive strategies.

Предметные рубрики MeSH

Alzheimer Disease Clinical Trials as Topic Cognition Dementia Exercise Therapy Humans Life Style Research Design Risk Reduction Behavior

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia.

Ошибки и ограничения

Аннотация

Предметные рубрики MeSH