Journal of neurology, neurosurgery, and psychiatry · 2009
The Severity of Dependence Scale detects people with medication overuse: the Akershus study of chronic headache.
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Grande R B, Aaseth K, Saltyte Benth J, Gulbrandsen P, Russell M B, Lundqvist C
Аннотация
OBJECTIVE: To evaluate the Severity of Dependence Scale (SDS) in people with primary chronic headache and analyse the pattern of medication overuse.
DESIGN: Cross sectional epidemiological survey. A posted questionnaire screened for chronic headache. Neurological residents interviewed those with self-reported chronic headache. The International Classification of Headache Disorders was used. Split file methodology was employed for data analysis.
SETTING: Akershus University Hospital, Oslo, Norway.
PARTICIPANTS: A random sample of 30,000 people, aged 30-44 years, from the general population of Akershus County, Norway. 405 people had primary chronic headache.
MAIN OUTCOME MEASURE: SDS score in those with and without medication overuse.
RESULTS: The screening questionnaire response rate was 71% and the participation rate of the interview 74%. Among 405 people with primary chronic headache, 95% had chronic tension-type headache, 4% had chronic migraine and <1% had other primary chronic headaches. Of 386 persons with chronic tension-type headache, 44% had medication overuse and 47% had co-occurrence of migraine. Simple analgesics, combination analgesics, triptans, ergotamine, opioids and a combination of acute medications were overused by 65%, 27%, 4%, <1%, 1% and 2% of people, respectively. The mean SDS score was significantly higher in those with than in those without medication overuse (5.6 vs 2.7; p<0.001).
CONCLUSION: The SDS questionnaire detects medication overuse and dependency-like behaviour in persons with primary chronic headache.
DESIGN: Cross sectional epidemiological survey. A posted questionnaire screened for chronic headache. Neurological residents interviewed those with self-reported chronic headache. The International Classification of Headache Disorders was used. Split file methodology was employed for data analysis.
SETTING: Akershus University Hospital, Oslo, Norway.
PARTICIPANTS: A random sample of 30,000 people, aged 30-44 years, from the general population of Akershus County, Norway. 405 people had primary chronic headache.
MAIN OUTCOME MEASURE: SDS score in those with and without medication overuse.
RESULTS: The screening questionnaire response rate was 71% and the participation rate of the interview 74%. Among 405 people with primary chronic headache, 95% had chronic tension-type headache, 4% had chronic migraine and <1% had other primary chronic headaches. Of 386 persons with chronic tension-type headache, 44% had medication overuse and 47% had co-occurrence of migraine. Simple analgesics, combination analgesics, triptans, ergotamine, opioids and a combination of acute medications were overused by 65%, 27%, 4%, <1%, 1% and 2% of people, respectively. The mean SDS score was significantly higher in those with than in those without medication overuse (5.6 vs 2.7; p<0.001).
CONCLUSION: The SDS questionnaire detects medication overuse and dependency-like behaviour in persons with primary chronic headache.
Предметные рубрики MeSH
AdultAnalgesicsAnalgesics, OpioidAnalysis of VarianceComorbidityCross-Sectional StudiesDrug Therapy, CombinationErgotamineFemaleHeadache DisordersHumansMaleMigraine DisordersNorwaySeverity of Illness IndexSubstance-Related DisordersSurveys and QuestionnairesTension-Type HeadacheTreatment OutcomeTryptamines