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DOI 10.1016/j.jpedsurg.2021.02.057

Медицинская библиотека · Journal of pediatric surgery · 2021

Outpatient parathyroidectomy in the pediatric population: An 18-year experience.

Ramonell Kimberly M, Fazendin Jessica, Lovell Kelly, Iyer Pallavi, Chen Herbert, Lindeman Brenessa, Dream Sophie

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Аннотация

BACKGROUND

Parathyroidectomy for primary hyperparathyroidism (pHPT) is safely performed in the outpatient setting in the adult population. However, concern that children and adolescents have higher complication rates and are unable to recognize and communicate symptoms of hypocalcemia has limited same-day discharges in the pediatric population.

METHODS

Nineteen patients aged 8-18 years (14.1 ± 0.7) underwent outpatient parathyroidectomy for pHPT by a single high-volume endocrine surgeon from 2002-2020. Patient demographics, disease, operations, and complications were reviewed.

RESULTS

Sixteen of 19 patients were symptomatic with fatigue (62.5%), joint pain (37.5%) and nephrolithiasis (18.7%) most common. Mean preoperative Ca and PTH were 11.7 ± 0.3 mg/dL and 102.3 ± 11.8pg/mL, respectively. Ten of 19 had a single adenoma and 9 had multigland hyperplasia including one MEN1 and one MEN2A patient. We performed 11 four-gland explorations, 8 unilateral parathyroidectomies; including 9 transcervical thymectomies, 1 total thyroidectomy, and 1 bilateral central neck dissection. Mean 6-month postoperative Ca and PTH levels were 9.5 ± 0.3 mg/dL (range 7.3-10.3) and 29±5.0pg/mL (range 6.3-77), respectively. One patient developed permanent hypoparathyroidism and 1 had temporary hypocalcemia. No temporary or permanent hoarseness, unplanned same-day admission, wound complications, or Emergency Department visits occurred.

CONCLUSION

Outpatient parathyroidectomy can be safely and effectively performed in pediatric patients with primary HPT.

LEVEL OF EVIDENCE: Treatment Study, Level III.

Для цитирования: Ramonell Kimberly M, Fazendin Jessica, Lovell Kelly, Iyer Pallavi, Chen Herbert, Lindeman Brenessa, Dream Sophie. Outpatient parathyroidectomy in the pediatric population: An 18-year experience.. Journal of pediatric surgery. 2021. DOI: 10.1016/j.jpedsurg.2021.02.057.

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