BMC cancer · 2006
An unusual cause of alveolar hemorrhage post hematopoietic stem cell transplantation: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Gupta Sachin, Jain Amit, Fanning Tina V, Couriel Daniel R, Jimenez Carlos A, Eapen Georgie A
Аннотация
BACKGROUND: Hematopoietic stem cell transplantation is being increasingly used in cancer therapy. Diffuse alveolar hemorrhage, an early complication of stem cell transplant, results from bacterial, viral and fungal infections, coagulopathy, and engraftment syndrome, or can be idiopathic. Diffuse alveolar hemorrhage associated with Strongyloides stercoralis hyperinfection in stem cell transplant patients has been rarely reported.
CASE PRESENTATION: We describe an unusual cause of alveolar hemorrhage post hematopoietic stem cell transplant due to Strongyloides hyperinfection. Therapy with parenteral ivermectin and thiabendazole was initiated but the patient deteriorated and died of respiratory failure and septic shock.
CONCLUSION: Strongyloides stercoralis hyperinfection is an unusual cause of alveolar hemorrhage early after hematopoietic stem cell transplant with very high mortality.
CASE PRESENTATION: We describe an unusual cause of alveolar hemorrhage post hematopoietic stem cell transplant due to Strongyloides hyperinfection. Therapy with parenteral ivermectin and thiabendazole was initiated but the patient deteriorated and died of respiratory failure and septic shock.
CONCLUSION: Strongyloides stercoralis hyperinfection is an unusual cause of alveolar hemorrhage early after hematopoietic stem cell transplant with very high mortality.
Предметные рубрики MeSH
AnimalsAnti-Infective AgentsAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyFatal OutcomeHematopoietic Stem Cell TransplantationHemorrhageHumansImmunocompromised HostIvermectinKlebsiella InfectionsLung Diseases, ParasiticLymphoma, FollicularMaleMiddle AgedPostoperative ComplicationsPulmonary AlveoliSepsisShock, SepticStrongyloides stercoralisStrongyloidiasisThiabendazole