Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit · 2001
The role of vitamin A in enhancing humoral immunity produced by antirabies vaccine.
Клиническое исследованиеСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Siddiqui F Q, Ahmad M M, Kakar F, Akhtar S, Dil A S
Аннотация
We tested the effects of vitamin A supplementation on the antibody titre of 40 healthy volunteers (age range: 10-35 years), who had received a complete course of antirabies vaccine (5 injections over 30 days). After determining the baseline serum vitamin A status of 80 volunteers, 20 pairs were matched for serum vitamin A level, body mass index, age, sex and socioeconomic status. One person from each pair was randomly assigned to an experimental or control group. The experimental group received vitamin A and antirabies vaccine. Controls received only the vaccine. The experimental group had significantly greater (2.1 times) serum antirabies titre than controls. This finding is an important step towards improving the economy of dosage of antirabies vaccines.
Предметные рубрики MeSH
AdolescentAdultAntibodies, ViralAntibody FormationBody Mass IndexChildChromatography, High Pressure LiquidCombined Modality TherapyDietary SupplementsDrug SynergismEnzyme-Linked Immunosorbent AssayFemaleHumansImmunocompetenceMalePakistanRabies VaccinesRabies virusSocioeconomic FactorsSurveys and QuestionnairesTreatment OutcomeVaccinationVitamin AVitamin A Deficiency