Vestnik oftalmologii · 2026
[Dry eye disease in university students].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Yanchenko S V, Kharibova E A, Malyshev A V, Teshaev Sh Zh, Odilov M Yu, Ramazonova Sh Sh
Аннотация
OBJECTIVE: The study aimed to assess the prevalence of dry eye disease (DED) in university students, identify significant risk factors, and determine possible directions for therapeutic management.
MATERIAL AND METHODS: The study included 88 students from Bukhara State Medical Institute named after Abu Ali ibn Sino aged 18-28 years. During stage 1 (online screening), the prevalence of symptomatic DED was determined (criterion: OSDI>12), and the significance of risk factors was assessed. During stage 2, students with OSDI>12 underwent the Norn test, Schirmer I test, Korb compression test, and meibography for diagnosis of meibomian gland dysfunction (MGD); clinical signs of infestation (CSI) by D. folliculorum and allergic conjunctivitis (AC) were identified, and the prevalence of DED was determined according to the DEWS III criteria (OSDI>12 and tear film breakup time <10 s). Statistics: χ² test, calculation of the normalized Pearson`s contingency coefficient (C').
RESULTS: The prevalence of symptomatic DED was 72.7%. Significant associations were found with female sex (C'=0.413), screen time >6 h per day (C'=0.332), eyeliner use (C'=0.555), and mascara use (C'=0.404). According to the DEWS III criteria, DED was diagnosed in 52.3% of students, with predominance of the evaporative form. Among the risk factors, the most significant were MGD (C'=0.579), AC (C'=0.371), and CSI (C'=0.347).
CONCLUSIONS: According to the DEWS III criteria, DED was detected in 52.3% of students, evaporative DES predominated, and MGD was the most significant factor and may be considered a pathogenetic component of the disease. The findings support eyelid hygiene, including the use of Blepharogel Ochischenie cleansing gel, Blepharolosion lotion, Blepharosalfetka wipes, Blepharogel-1, Blepharogel-2, and Blepharogel Forte, as one of the potential components of comprehensive DED therapy in university students.
MATERIAL AND METHODS: The study included 88 students from Bukhara State Medical Institute named after Abu Ali ibn Sino aged 18-28 years. During stage 1 (online screening), the prevalence of symptomatic DED was determined (criterion: OSDI>12), and the significance of risk factors was assessed. During stage 2, students with OSDI>12 underwent the Norn test, Schirmer I test, Korb compression test, and meibography for diagnosis of meibomian gland dysfunction (MGD); clinical signs of infestation (CSI) by D. folliculorum and allergic conjunctivitis (AC) were identified, and the prevalence of DED was determined according to the DEWS III criteria (OSDI>12 and tear film breakup time <10 s). Statistics: χ² test, calculation of the normalized Pearson`s contingency coefficient (C').
RESULTS: The prevalence of symptomatic DED was 72.7%. Significant associations were found with female sex (C'=0.413), screen time >6 h per day (C'=0.332), eyeliner use (C'=0.555), and mascara use (C'=0.404). According to the DEWS III criteria, DED was diagnosed in 52.3% of students, with predominance of the evaporative form. Among the risk factors, the most significant were MGD (C'=0.579), AC (C'=0.371), and CSI (C'=0.347).
CONCLUSIONS: According to the DEWS III criteria, DED was detected in 52.3% of students, evaporative DES predominated, and MGD was the most significant factor and may be considered a pathogenetic component of the disease. The findings support eyelid hygiene, including the use of Blepharogel Ochischenie cleansing gel, Blepharolosion lotion, Blepharosalfetka wipes, Blepharogel-1, Blepharogel-2, and Blepharogel Forte, as one of the potential components of comprehensive DED therapy in university students.