Archives of virology · 2010
Comparative analysis of rabies virus isolates from Brazilian canids and bats based on the G gene and G-L intergenic region.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Carnieli Pedro, Fahl Willian de Oliveira, Brandão Paulo Eduardo, Oliveira Rafael de Novaes, Macedo Carla Isabel, Durymanova Ekaterina, Castilho Juliana Galera
Аннотация
Rabies virus (RABV) isolates from two species of canids and three species of bats were analyzed by comparing the C-terminal region of the G gene and the G-L intergenic region of the virus genome. Intercluster identities for the genetic sequences of the isolates showed both regions to be poorly conserved. Phylogenetic trees were generated by the neighbor-joining and maximum parsimony methods, and the results were found to agree between the two methods for both regions. Putative amino acid sequences obtained from the G gene were also analyzed, and genetic markers were identified. Our results suggest that different genetic lineages of RABV are adapted to different animal species in Brazil.