The American journal of tropical medicine and hygiene · 2011
Vernal keratoconjunctivitis in school children in Rwanda and its association with socio-economic status: a population-based survey.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Smedt Stefan De, Nkurikiye John, Fonteyne Yannick, Hogewoning Arjan, Esbroeck Marjan Van, Bacquer Dirk De, Tuft Stephen, Gilbert Clare, Delanghe Joris, Kestelyn Philippe
Аннотация
Vernal keratoconjunctivitis (VKC) is an allergic eye disease and an important cause of hospital referral among children in Africa and Asia. Hospital-based studies have suggested a role for parasites in its pathogenesis. To determine the prevalence and risk factors for VKC in Central Africa, we conducted a nested population-based case control study in Rwanda, involving randomly selected primary schools from different environments (rural/urban) and climate. A prevalence of VKC of 4.0% (95% confidence interval 3.3-4.7%) was found among 3,041 children studied (participation rate 94.7%). The intestinal parasitic burden was not related to VKC. Besides hot dry climate (odds ratio [OR] = 1.5, P = 0.05) and male gender (OR = 1.7, P = 0.005), multivariate analysis identified higher economic status as a risk for VKC (OR = 1.4, P = 0.005). The effect on VKC of higher economic status appears not to act through differences in parasitic intestinal load.