Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2007
Topical bromfenac sodium for long-term management of vernal keratoconjunctivitis.
СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Uchio Eiichi, Itoh Yuki, Kadonosono Kazuaki
Аннотация
BACKGROUND/AIMS: We evaluated the efficacy and safety of long-term management of patients with vernal keratoconjunctivitis (VKC) with bromfenac sodium eye drops in combination with corticosteroids and anti-allergic eye drops.
METHODS: Twenty-two patients with VKC were randomly assigned to receive two test eye drops, either bromfenac sodium 0.1% (group A) or placebo eye drops (normal saline; group B) for a mean observation period of 20.9 months. Topical corticosteroids and mast cell stabilizers were continued during the observation period.
RESULTS: The mean 2-year recurrence rate was 90.9% in group A and 11.3% in group B, with a significant difference. No serious side effect was observed in group A.
CONCLUSION: These results suggest that bromfenac sodium eye drops can be used as baseline local treatment in patients with VKC.
METHODS: Twenty-two patients with VKC were randomly assigned to receive two test eye drops, either bromfenac sodium 0.1% (group A) or placebo eye drops (normal saline; group B) for a mean observation period of 20.9 months. Topical corticosteroids and mast cell stabilizers were continued during the observation period.
RESULTS: The mean 2-year recurrence rate was 90.9% in group A and 11.3% in group B, with a significant difference. No serious side effect was observed in group A.
CONCLUSION: These results suggest that bromfenac sodium eye drops can be used as baseline local treatment in patients with VKC.
Предметные рубрики MeSH
AdolescentAdultAnti-Allergic AgentsAnti-Inflammatory Agents, Non-SteroidalBenzophenonesBromobenzenesChildChild, PreschoolConjunctivaConjunctivitis, AllergicCorneaDrug Administration ScheduleDrug Therapy, CombinationFemaleFollow-Up StudiesGlucocorticoidsHumansMaleOphthalmic SolutionsSeverity of Illness IndexTime FactorsTreatment Outcomeortho-Aminobenzoates