[Intraindividual Keratoconus Progression].

Introduction Keratoconus is a typically bilateral, progressive-extending corneal disease. The aim of this work is to evaluate the intraindividual progression of keratoconus. Patients and Methods This single-center retrospective study of disease progression based on topographic data from non-operated keratoconus patients (n = 48) was examined over a period of two years. Seven topographical keratoconus indices derived from Scheimpflug tomography were used to compare both the initial findings, as well as the progression of the fellow eyes. Results The mean observation period was 3.3 ± 0.9 years. The initial findings illustrated that a pair of eyes did not correlate with each other (p > 0.05). When comparing baseline and the progression of the individual indices, a negative correlation was found for all indices (p < 0.05). Progression and age did correlate for index smallest radius (Rmin, (R = 0.376, p = 0.008) and index of height decentration (IHD, R = 0.291, p = 0.045). Regarding the intraindividual progression, we found a weak correlation to the index of surface variance (ISV, R = - 0.399, p = 0.005), index of vertical asymmetry (IVA, R = - 0.291, p = 0.045) and the keratoconus index (KI, R = 0.307, p = 0.038). Conclusions The intraindividual asymmetry, which is typical for keratoconus, could be verified. This study suggests that the progression of keratoconus in one eye is independent of the progression in the fellow eye. In this small group of patients, age relationship to keratoconus could not be demonstrated for all keratoconus indices.