Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) · 2009
[Sensitization to three species of mites in allergic patients from the coastal area of Havana city].
Сравнительное исследованиеАннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Almarales Raúl L Castro, Castelló Mirta Alvarez, Díaz Mercedes Ronquillo, Canosa José S Rodríguez, Gómez Iris García, León Mayda González, Domínguez Irene Enríquez, Rosado Alexis Labrada, Viltre Bárbara I Navarro, Díaz Yunia Oliva, Morejón Maytee Mateo
Аннотация
BACKGROUND: Sensitization to three allergic mite species (Dermatophagoides pteronyssinus, Dermatophagoides siboney and Blomia tropicalis) from house dust in Cuba has been reported in different studies.
OBJECTIVE: To assess allergic sensitization to these mites in a north coast area of Havana city.
PATIENTS AND METHODS: A total of 210 allergic patients were selected, classified in two groups: from 1 to 14 years, and from 15 to 55 years. Skin Prick Test (SPT) was performed on all patients using standardized allergenic extracts VALERGEN-BT (B. tropicalis), VALERGEN-DS (D. siboney) and VALERGEN-DP (D. pteronyssinus) manufactured by BIOCEN, Cuba. The test was considered positive when the average wheal diameter was greater or equal to 3 mm.
RESULTS: Both groups showed higher sensitization to D. pteronyssinus (>78%), while for the remaining mites it was below 60%. In patients older than 14 years, the sensitization was apparently higher, although not statistically significant (p > 0.05). Nevertheless, the skin reactivity in this group was significantly greater (p < 0.05) for the three allergens. Unusually, mean wheal size in both groups was significantly superior toward B. tropicalis (p < 0.05).
CONCLUSIONS: In spite of being D. pteronyssinus the mite showing the highest sensitization, Blomia tropicalis showed to be also an important aeroallergen with more than 50% sensitization and greater skin reactivity. Therefore, in our population it would be advisable to perform SPT with the three mites extracts, simultaneously and to combine it in allergen-specific immunotherapy.
OBJECTIVE: To assess allergic sensitization to these mites in a north coast area of Havana city.
PATIENTS AND METHODS: A total of 210 allergic patients were selected, classified in two groups: from 1 to 14 years, and from 15 to 55 years. Skin Prick Test (SPT) was performed on all patients using standardized allergenic extracts VALERGEN-BT (B. tropicalis), VALERGEN-DS (D. siboney) and VALERGEN-DP (D. pteronyssinus) manufactured by BIOCEN, Cuba. The test was considered positive when the average wheal diameter was greater or equal to 3 mm.
RESULTS: Both groups showed higher sensitization to D. pteronyssinus (>78%), while for the remaining mites it was below 60%. In patients older than 14 years, the sensitization was apparently higher, although not statistically significant (p > 0.05). Nevertheless, the skin reactivity in this group was significantly greater (p < 0.05) for the three allergens. Unusually, mean wheal size in both groups was significantly superior toward B. tropicalis (p < 0.05).
CONCLUSIONS: In spite of being D. pteronyssinus the mite showing the highest sensitization, Blomia tropicalis showed to be also an important aeroallergen with more than 50% sensitization and greater skin reactivity. Therefore, in our population it would be advisable to perform SPT with the three mites extracts, simultaneously and to combine it in allergen-specific immunotherapy.