Radiology · 1993
Irradiation of the cervix uteri: value of unenhanced and contrast-enhanced MR imaging.
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Hricak H, Swift P S, Campos Z, Quivey J M, Gildengorin V, Göranson H
Аннотация
PURPOSE: To analyze the value of magnetic resonance (MR) imaging after radiation therapy for cancer of the cervix.
MATERIALS AND METHODS: Eighty-nine MR images were retrospectively studied in 69 patients aged 46.3 years +/- 11.5. MR findings of tumor recurrence and irradiation changes were correlated with time after radiation therapy; paracentral radiation dose (dose to point A); and in patients with pretreatment images, primary tumor size and stage.
RESULTS: Overall accuracy of MR in diagnosis of tumor recurrence was 78% (positive predictive value, 65%; negative predictive value, 97%). In MR examinations less than 6 months after the beginning of radiation therapy, accuracy (69%) and specificity (46%) were significantly lower than in examinations more than 6 months later (88%, P = .0032; 81%, P = .0166, respectively). Comparison of pre- and posttreatment MR findings and knowledge of stage or initial tumor size did not affect MR results.
CONCLUSION: Overall, diagnosis was best with unenhanced T2-weighted images, but in patients with adnexal or pelvic sidewall recurrence and in patients with treatment complications (eg, fistula formation), contrast enhancement did help.
MATERIALS AND METHODS: Eighty-nine MR images were retrospectively studied in 69 patients aged 46.3 years +/- 11.5. MR findings of tumor recurrence and irradiation changes were correlated with time after radiation therapy; paracentral radiation dose (dose to point A); and in patients with pretreatment images, primary tumor size and stage.
RESULTS: Overall accuracy of MR in diagnosis of tumor recurrence was 78% (positive predictive value, 65%; negative predictive value, 97%). In MR examinations less than 6 months after the beginning of radiation therapy, accuracy (69%) and specificity (46%) were significantly lower than in examinations more than 6 months later (88%, P = .0032; 81%, P = .0166, respectively). Comparison of pre- and posttreatment MR findings and knowledge of stage or initial tumor size did not affect MR results.
CONCLUSION: Overall, diagnosis was best with unenhanced T2-weighted images, but in patients with adnexal or pelvic sidewall recurrence and in patients with treatment complications (eg, fistula formation), contrast enhancement did help.
Предметные рубрики MeSH
AdenocarcinomaCarcinoma, Squamous CellCervix UteriContrast MediaDrug CombinationsEndometriumFemaleFollow-Up StudiesGadoliniumGadolinium DTPAHumansImage EnhancementLymph NodesMagnetic Resonance ImagingMeglumineMiddle AgedNeoplasm InvasivenessNeoplasm Recurrence, LocalOrganometallic CompoundsPentetic AcidRadiation InjuriesRadiotherapy DosageRetrospective StudiesTime FactorsUterine Cervical Neoplasms