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Войти в исследования The International journal of neuroscience · 2014
Occurrence of Hashimoto's thyroiditis among the patients with Sydenham's chorea.
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Dai Alper I, Demiryürek Seniz, Keskin Mehmet, Demiryürek Abdullah T
Аннотация
AIM: The purpose of this study was to examine the possible association of Hashimoto's thyroiditis (HT) with Sydenham's chorea (SC).
MATERIALS AND METHODS: A total of 25 SC patients and 25 patients with the diagnosis of HT were included in the study. Neurological, cardiac, radiological abnormalities, clinical findings, and biochemical analysis were evaluated.
RESULTS: Heart murmur as a result of mitral valve deformation was present in all SC group patients. No neurologic and cardiac abnormalities were noted in HT group. Serum thyroid-stimulating hormone (TSH), anti-thyroid peroxidase, and anti-thyroglobulin levels were found to be high in 4 patients of the SC group and called as SC with HT group. Significant elevation of serum TSH levels in SC with HT group (31.75 ± 3.71 μU/ml) was observed when compared to HT group (12.60 ± 4.24 μU/ml, p < 0.05).
CONCLUSION: These results showed that HT can be occurred among the patients with SC with cardiac involvement.
MATERIALS AND METHODS: A total of 25 SC patients and 25 patients with the diagnosis of HT were included in the study. Neurological, cardiac, radiological abnormalities, clinical findings, and biochemical analysis were evaluated.
RESULTS: Heart murmur as a result of mitral valve deformation was present in all SC group patients. No neurologic and cardiac abnormalities were noted in HT group. Serum thyroid-stimulating hormone (TSH), anti-thyroid peroxidase, and anti-thyroglobulin levels were found to be high in 4 patients of the SC group and called as SC with HT group. Significant elevation of serum TSH levels in SC with HT group (31.75 ± 3.71 μU/ml) was observed when compared to HT group (12.60 ± 4.24 μU/ml, p < 0.05).
CONCLUSION: These results showed that HT can be occurred among the patients with SC with cardiac involvement.