Медицинская библиотека · Zhongguo yi miao he mian yi · 2009

[Safety and immunogenicity of rabies vaccine (chick embryo cell) for human use produced in Germany and India].

Zhu Feng-Cai, Wu Chuan-Hong, Meng Fan-Yue

Аннотация на английскомСтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

OBJECTIVE

To evaluate the safety and immunogenicity of Rabipur produced in India.

METHODS

A random and single-blind study was conducted to compare the safety, effect and sero conversion rates. Rabipur produced in Germany used as control group.

RESULTS

The results showed that they were no severe systemic and local reaction occurred in trial group (Rabipur produced in India). The difference between trial group and control group was not significant. 14 day and 45 days after the first dose, the seroconversion rates of the two groups were 100%. 14 day and 45 days after the first dose, GMC of the two groups increased obviously and highly beyond 0.5TU/ml.

CONCLUSION

Rabipur produced in India has excellent safety and immunogenicity. Trial Registration National Food Drugs Surveillance Administrative Bureau, "Medicine Clinical Experiment Written directive from a superior" 2005L04184.

Для цитирования: Zhu Feng-Cai, Wu Chuan-Hong, Meng Fan-Yue. [Safety and immunogenicity of rabies vaccine (chick embryo cell) for human use produced in Germany and India].. Zhongguo yi miao he mian yi. 2009.

Предметные рубрики MeSH

Adolescent Adult Animals Antibodies, Viral Chick Embryo Child Drug-Related Side Effects and Adverse Reactions Female Germany Humans India Male Middle Aged Rabies Rabies Vaccines Rabies virus Young Adult

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