Physical activity of children with a mitochondrial disease compared to children who are healthy.

PURPOSE: To compare the physical activity of a group of children with mitochondrial myopathy (MM) with children who are healthy and to evaluate the suitability of different measurement tools.

METHODS

The physical activity of 6 children with MM and 10 children who are healthy was measured using accelerometry, heart rate monitoring, video observation, rating of their fatigue, and 2 questionnaires about their physical activity and quality of life.

RESULTS

The children with MM spent less time in moderate to vigorous activity, and their activity level measured with the accelerometer was lower than the children who are healthy. Also, the children with MM indicated a higher level of fatigue and a lower quality of life.

CONCLUSIONS

Children with MM are on average less physically active, report a higher level of fatigue, and a lower quality of life than children who are healthy.