Creutzfeld-Jakob disease: clinical, EEG and neuropathological findings in a cluster of eleven patients.

10 of 11 Creutzfeld-Jakob disease patients were seen between February 1975 and November 1979. Whilst the clinical and EEG findings were uniform, the neuropathological changes were not: astrogliosis was always diffuse and widespread but the other typical changes (neuronal loss and spongiosis) varied greatly both in degree and location.