Terapevticheskii arkhiv · 2000
[Circadian structure of cardiac rhythm in tachyarrhythmia].
Сравнительное исследованиеАннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Makarov L M, Shkol'nikova M A, Bereznitskaia V V, Kuryleva T A, Chuprova S N
Аннотация
AIM: To determine clinical implication of changes in the structure of circadian cardiac rhythm in patients with tachyarrhythmia basing on estimation of the circadian index (CI).
MATERIAL AND METHODS: 24-h Holter monitoring was conducted in 154 patients aged 4 to 18 years: 125--with supraventricular paroxysmal tachycardia, 13--with long Q-T interval, 16--with idiopathic ventricular tachycardia. CI was calculated as mean day heart rate (from 7.00 to 22.00)/mean night heart rate (from 23.00 to 6.00).
RESULTS: Patients with long Q-T interval had less CI while those with supraventricular paroxysmal and idiopathic ventricular tachycardia had higher CI vs normal values. CI changes became more pronounced with growing disease severity.
CONCLUSION: Cardiac arrhythmia with low CI is associated with progressive vegetative denervation while that with high CI occurs in increased cardiac sensitivity to sympathetic impacts.
MATERIAL AND METHODS: 24-h Holter monitoring was conducted in 154 patients aged 4 to 18 years: 125--with supraventricular paroxysmal tachycardia, 13--with long Q-T interval, 16--with idiopathic ventricular tachycardia. CI was calculated as mean day heart rate (from 7.00 to 22.00)/mean night heart rate (from 23.00 to 6.00).
RESULTS: Patients with long Q-T interval had less CI while those with supraventricular paroxysmal and idiopathic ventricular tachycardia had higher CI vs normal values. CI changes became more pronounced with growing disease severity.
CONCLUSION: Cardiac arrhythmia with low CI is associated with progressive vegetative denervation while that with high CI occurs in increased cardiac sensitivity to sympathetic impacts.