[Pathogenetic and clinical aspects of Fisher syndrome].

Fisher syndrome has a triad of signs: ophthalmoplegia, ataxia and areflexia. In view of the evidence of peripheral nervous system involvement it resembles atypical forms of the Guillain-Barré syndrome. In 1956 Fisher isolated the syndrome as a separate nosological entity calling attention to involvement of central structures. The review of the reports on the syndrome suggests that its pathological mechanism is mixed, with involvement of peripheral and central structures.