Zhonghua er bi yan hou ke za zhi · 2001
[Roles of CD43, CD20 and local IgE in the pathogenesis of nasal polyps].
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Wang X, Guo J, Zhang H, Tao G, Han D, Zhu X, Fan E, Li Y
Аннотация
OBJECTIVE: To estimate the roles of CD43, CD20 and total IgE in the pathogenesis of nasal polyps.
METHOD: Twenty-six cases of nasal polyps and 20 cases of mucosa of middle turbinates were used in present study.
RESULTS: The number of CD43+ cells, CD20+ cells and plasma cells in nasal polyps were significantly more than that in middle turbinates (P < 0.01). The positive rate of local IgE+ cells in nasal polyps was significantly higher than in middle turbinate (P < 0.01).
CONCLUSION: There were active cellular immunity and humoral immunity in nasal polyps. Local allergy may play a role in the pathogenesis of nasal polyps.
METHOD: Twenty-six cases of nasal polyps and 20 cases of mucosa of middle turbinates were used in present study.
RESULTS: The number of CD43+ cells, CD20+ cells and plasma cells in nasal polyps were significantly more than that in middle turbinates (P < 0.01). The positive rate of local IgE+ cells in nasal polyps was significantly higher than in middle turbinate (P < 0.01).
CONCLUSION: There were active cellular immunity and humoral immunity in nasal polyps. Local allergy may play a role in the pathogenesis of nasal polyps.