Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2000
[Detection of Epstein-Barr virus and human papillomavirus in sinonasal malignant neoplasms].
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Gao P F, Chen W X, Xiao L Y, Yan X J
Аннотация
OBJECTIVE: To investigate the existance of Epstein-Barr virus (EBV) and papilloma virus(HPV) in sinonasal malignant neoplasms.
METHOD: EBV and HPV (including HPV6,11,16,18,33) gene were detected in paraffin-embedded tissues with polymerase chain reaction(PCR) from 32 cases of sinonasal malignant neoplasms.
RESULT: EBV was detected in 12(37.5%), HPV in 21(65.6%); The coinfection of EBV and HPV was found in 6 cases with stage III-IV by TNM; 10 cases of nasal polyps contained neither EBV nor HPV.
CONCLUSION: Like HPV, there may be relationship between EBV and sinonasal malignant neoplasms. The coinfection of EBV and HPV is related to stage III-IV by TNM of sinonasal malignant neoplasms.
METHOD: EBV and HPV (including HPV6,11,16,18,33) gene were detected in paraffin-embedded tissues with polymerase chain reaction(PCR) from 32 cases of sinonasal malignant neoplasms.
RESULT: EBV was detected in 12(37.5%), HPV in 21(65.6%); The coinfection of EBV and HPV was found in 6 cases with stage III-IV by TNM; 10 cases of nasal polyps contained neither EBV nor HPV.
CONCLUSION: Like HPV, there may be relationship between EBV and sinonasal malignant neoplasms. The coinfection of EBV and HPV is related to stage III-IV by TNM of sinonasal malignant neoplasms.