Oral surgery, oral medicine, oral pathology and oral radiology · 2012
Oral manifestations in patients with hypogammaglobulinemia.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Fernandes Karin Sá, Kokron Cristina Maria, Barros Myrthes Toledo, Kalil Jorge, Gallottini Marina
Аннотация
OBJECTIVE: The overall objective of this study was to assess the oral manifestations and their association with immunologic status and health history, of individuals with hypogammaglobulinemia.
STUDY DESIGN: A case-controlled study of 100 subjects with hypogammaglobulinemia and 93 control individuals was performed. All participants were examined for dental caries, periodontal disease, mucosal lesions/infections, and general oral health problems. Decayed, missing, filled teeth and community periodontal index were recorded. Complete blood count, serum immunoglobulins, and lymphocyte immunophenotyping were measured on the same day of the oral health assessment.
RESULTS: Individuals with hypogammaglobulinemia showed higher prevalence of enamel hypoplasia and complaints of dry mouth, and lower prevalence of dental caries and periodontal disease.
CONCLUSIONS: The systemic conditions associated with hypogammaglobulinemia were not associated with enhanced susceptibility to caries, gingivitis, or periodontitis; however, individuals with hypogammaglobulinemia were more likely to report more episodes of recurrent aphthous ulcers compared with control individuals.
STUDY DESIGN: A case-controlled study of 100 subjects with hypogammaglobulinemia and 93 control individuals was performed. All participants were examined for dental caries, periodontal disease, mucosal lesions/infections, and general oral health problems. Decayed, missing, filled teeth and community periodontal index were recorded. Complete blood count, serum immunoglobulins, and lymphocyte immunophenotyping were measured on the same day of the oral health assessment.
RESULTS: Individuals with hypogammaglobulinemia showed higher prevalence of enamel hypoplasia and complaints of dry mouth, and lower prevalence of dental caries and periodontal disease.
CONCLUSIONS: The systemic conditions associated with hypogammaglobulinemia were not associated with enhanced susceptibility to caries, gingivitis, or periodontitis; however, individuals with hypogammaglobulinemia were more likely to report more episodes of recurrent aphthous ulcers compared with control individuals.
Предметные рубрики MeSH
AdolescentAdultAgammaglobulinemiaAgedB-LymphocytesBlood Cell CountCD3 ComplexCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCase-Control StudiesDMF IndexDental CariesDental Enamel HypoplasiaFemaleHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MKiller Cells, NaturalMaleMiddle AgedMouth DiseasesPeriodontal DiseasesPeriodontal IndexStomatitis, AphthousStomatitis, HerpeticT-LymphocytesXerostomiaYoung Adult