Journal of the American Board of Family Medicine : JABFM · 2016
Probability of Vitamin D Deficiency by Body Weight and Race/Ethnicity.
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Weishaar Tom, Rajan Sonali, Keller Bryan
Аннотация
INTRODUCTION: While most physicians recognize that vitamin D status varies by skin color because darker skin requires more light to synthesize vitamin D than lighter skin, the importance of body weight to vitamin D status is a newer, less recognized, finding. The purpose of this study was to use nationally representative US data to determine the probability of vitamin D deficiency by body weight and skin color.
METHODS: Using data for individuals age ≥6 years from the 2001 to 2010 cycles of the US National Health and Nutrition Examination Survey, we calculated the effect of skin color, body weight, and age on vitamin D status. We determined the probability of deficiency within the normal range of body weight for 3 race/ethnicity groups at 3 target levels of 25-hydroxyvitamin D.
RESULTS: Darker skin colors and heavier body weights are independently and significantly associated with poorer vitamin D status. We report graphically the probability of vitamin D deficiency by body weight and skin color at vitamin D targets of 20 and 30 ng/mL.
CONCLUSION: The effects of skin color and body weight on vitamin D status are large both statistically and clinically. Knowledge of these effects may facilitate diagnosis of vitamin D deficiency.
METHODS: Using data for individuals age ≥6 years from the 2001 to 2010 cycles of the US National Health and Nutrition Examination Survey, we calculated the effect of skin color, body weight, and age on vitamin D status. We determined the probability of deficiency within the normal range of body weight for 3 race/ethnicity groups at 3 target levels of 25-hydroxyvitamin D.
RESULTS: Darker skin colors and heavier body weights are independently and significantly associated with poorer vitamin D status. We report graphically the probability of vitamin D deficiency by body weight and skin color at vitamin D targets of 20 and 30 ng/mL.
CONCLUSION: The effects of skin color and body weight on vitamin D status are large both statistically and clinically. Knowledge of these effects may facilitate diagnosis of vitamin D deficiency.