Frontiers in public health · 2026
Microplastics in neonates: an overlooked cost of parenteral nutrition.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Xu Debo, Liang Zhenyu, Yang Qiaohuan, Li Lin, Li Huiyi, You Chuming, Meng Qiong, Zhou Wei
Аннотация
INTRODUCTION: Microplastics (MPs) are emerging contaminants that raise concerns due to their potential health effects on vulnerable neonates who may be exposed to medical devices.
METHODS: This prospective study investigated the presence of MPs in neonatal blood in relation to parenteral nutrition (PN) duration. A total of 12 neonates were categorized into long-term (>14 days), short-term (3-7 days), and non-exposed control groups. MPs were analyzed using confocal micro-Raman spectroscopy.
RESULTS: Polyethylene accounted for 95.65% of particles detected in all blood samples. MP abundance was significantly higher in the long-term PN group compared to both short-term and control groups (p < 0.05), demonstrating a dose-response relationship with PN duration. Notably, larger MPs (>60 μm) were found exclusively in the long-term group.
DISCUSSION: These preliminary findings, derived from a small sample cohort, suggest that the PN system may serve as a potential iatrogenic source of MPs for neonates.
CLINICAL TRIAL REGISTRATION: NCT07326761.
METHODS: This prospective study investigated the presence of MPs in neonatal blood in relation to parenteral nutrition (PN) duration. A total of 12 neonates were categorized into long-term (>14 days), short-term (3-7 days), and non-exposed control groups. MPs were analyzed using confocal micro-Raman spectroscopy.
RESULTS: Polyethylene accounted for 95.65% of particles detected in all blood samples. MP abundance was significantly higher in the long-term PN group compared to both short-term and control groups (p < 0.05), demonstrating a dose-response relationship with PN duration. Notably, larger MPs (>60 μm) were found exclusively in the long-term group.
DISCUSSION: These preliminary findings, derived from a small sample cohort, suggest that the PN system may serve as a potential iatrogenic source of MPs for neonates.
CLINICAL TRIAL REGISTRATION: NCT07326761.