Reduced concentrations of ascorbic acid and glutathione in a single case of Rett syndrome: a postmortem brain study.

Preliminary data of a postmortem brain study in a single case with Rett syndrome compared to a single control case showed a severe reduction of ascorbic acid and reduced glutathione in most brain regions studied. These findings suggest a secondary disturbance of ascorbic acid and glutathione metabolism in the Rett syndrome.