Медицинская библиотека · Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae · 2001

[Clinical value of induced sputum test in monitoring airway inflammation in asthma].

Zhang H B, Lin Y G, Zhao X M

Сравнительное исследованиеАннотация на английскомСтатьяПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

OBJECTIVE

To explore the clinical value of induced sputum test in monitoring airway inflammation in asthmatic patients.

METHODS

The induced sputum test was done in 12 normal subjects and 21 asthmatic subjects; The levels of interleukin-8 (IL-8), eosinophil cation protein (ECP), malondialdehyde (MDA) in plasma and induced sputum in all subjects were measured.

RESULTS

The levels of IL-8, ECP, MDA in plasma and induced sputum in unstable asthmatic patients were significantly higher than those in stable asthmatic (P < 0.01), in which the levels of IL-8, ECP, MDA in both plasma and induced sputum were significantly higher than those in normal subjects(P < 0.05); In all asthmatic patients, the levels of IL-8, ECP, MDA in induced sputum were significantly higher than those in plasma.

CONCLUSION

The levels of IL-8, ECP, MDA in induced sputum could be used for monitoring airway inflammation in asthmatic patients.

Для цитирования: Zhang H B, Lin Y G, Zhao X M. [Clinical value of induced sputum test in monitoring airway inflammation in asthma].. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2001.

Предметные рубрики MeSH

Adult Asthma Blood Proteins Bronchi Eosinophil Granule Proteins Humans Inflammation Interleukin-8 Malondialdehyde Ribonucleases Sputum

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