JAMA dermatology · 2013
Finasteride for the treatment of hidradenitis suppurativa in children and adolescents.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Randhawa Harkamal Kaur, Hamilton Jill, Pope Elena
Аннотация
IMPORTANCE: Hidradenitis suppurativa (HS) is a chronic debilitating cutaneous disease for which there is no universally effective treatment. Patients typically present at puberty with tender subcutaneous nodules that can progress to dermal abscess formation. Antiandrogens have been used in the treatment of HS, and studies have primarily focused on adult patients.
OBSERVATIONS: We present a case series of 3 pediatric patients with HS who were successfully treated with oral finasteride, resulting in decreased frequency and severity of disease flares with no significant adverse effects.
CONCLUSIONS AND RELEVANCE: Finasteride is a therapeutic option that provides benefit for pediatric patients with HS. Further prospective data and randomized controlled studies will provide helpful information in the management of this disease.
OBSERVATIONS: We present a case series of 3 pediatric patients with HS who were successfully treated with oral finasteride, resulting in decreased frequency and severity of disease flares with no significant adverse effects.
CONCLUSIONS AND RELEVANCE: Finasteride is a therapeutic option that provides benefit for pediatric patients with HS. Further prospective data and randomized controlled studies will provide helpful information in the management of this disease.