Journal of occupational medicine. : official publication of the Industrial Medical Association · 1993
Patients with suspected solvent-induced encephalopathy examined with cerebral computed tomography.
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Ellingsen D G, Bekken M, Kolsaker L, Langård S
Аннотация
The aim of this study was to investigate the relationship between organic solvent exposure and brain atrophy among 85 patients referred to a department of occupational medicine and who underwent cerebral computed tomography. On average, the patients had been heavily exposed to a mixture of organic solvents for 22.9 years. Diseases which may be associated with brain atrophy or high alcohol consumption was observed among 31% of the subjects. Among these subjects the prevalence of brain atrophy was 58%. The prevalence of brain atrophy was 20% among the men without such conditions. None of the eight female patients appeared to have atrophy. The quantitative assessment showed no correlation between the duration of exposure and atrophy-related parameters. However, the width of the third ventricle, bifrontal ratio, and bicaudate ratio were correlated with age.